RESEARCH AND CREATIVE WORK

IPA Recipients for April 2018

Fig. 1. The unfolded protein response (UPR) activates pathways dedicated to cell survival and cell death. In the presence of aberrations, HSP90 dissociates from PERK that then phosphorylates eIF2α to attenuate protein translation. Likewise, it activates ATF4 that induces the transcription of CHOP – an apoptotic signal, and miR-211 that controls it. miR-211 acts as a molecular switch, which downregulates during persistent stress, allowing CHOP to accumulate and mediate apoptosis. On the other hand, unfolded proteins activate IRE1 that upon autophosphorylation induces splicing of Xbp1, which assists protein folding and degradation.

Rafael Vincent M. Manalo and Paul Mark B. Medina Department of Biochemistry and Molecular Biology College of Medicine UP Manila The Endoplasmic Reticulum Stress Response in Disease Pathogenesis and Pathophysiology. Egyptian Journal of Medical Human Genetics, 19 (2): 59-68, April 2018. Many disease of epidemiologic significance, such as infectious and non-communicable diseases, are almost always studied separately. However, the tissues affected in all of these diseases — be it neuronal, muscular, epithelial or connective – all have one thing in common: they all have an endoplasmic reticulum (ER). Surprisingly, this organelle is the principal actor in disease, since it acts to […]

Six UP researchers, graduates among the eight Filipinos in Asian Scientist 100

Six UP researchers, graduates among the eight Filipinos in Asian Scientist 100

Six UP faculty members and alumni are in the 2018 edition of the Asian Scientist 100, a handpicked selection of Asian researchers in the Asia Pacific region who have been competitively chosen for prestigious scientific awards or have made major scientific contributions. Dr. Aletta T. Yñiguez (assistant professor, Marine Science Institute, UP Diliman), Dr. Phillip A. Alviola (associate professor, Institute of Biological Sciences, UP Los Baños and curator, UP Los Baños Museum of Natural History) and Dr. Nathaniel P. Hermosa II (associate professor, National Institute of Physics, UP Diliman) are among the eight Filipinos featured in the latest list. Yñiguez, […]

57th UPNWW lectures: Staying lit and legit in the era of fake news and mistranslations of mythology in Philippine popular culture

57th UPNWW lectures: Staying lit and legit in the era of fake news and mistranslations of mythology in Philippine popular culture

What is the role of writers in a fake news and post-truth era? How is mythology seen in Philippine pop culture today?   These intriguing questions will be discussed by poet and critic Dr. J. Neil Garcia and playwright Eljay Castro Deldoc at the Abraham Sarmiento Hall, UP Baguio, at 1:30 – 4:30 pm on 4 April 2018. The lectures are free of charge and open to the public.    Dr. Garcia will speak on “Mythopoeia and Communal Subjectivity: Mistranslations of Mythology in Philippine Popular Culture.” Deldoc will tell us how to “Be Lit and Legit sa Mundong Full of Clickbait and Shi*t”. J. Neil C. Garcia teaches […]

IPA Recipients for March 2018

IPA Recipients for March 2018

Richard Espiritu Department of Mining, Metallurgical and Materials Engineering College of Engineering UP Diliman Degradation of Radiation Grafted Anion Exchange Membranes Tethered with Different Amine Functional Groups Via Removal of Vinylbenzyl Trimethylammonium Hydroxide. Journal of Power Sources, 375: 373-386, 31 January 2018. The chemical stability of anion exchange membranes (AEM), particularly at high operating temperatures, poses a critical challenge that limits the wide scale use of alkaline fuel cells. Thus, a fundamental understanding of the chemical stability of anion exchange membranes is required to adequately design robust solid-state anion exchange membrane for electrolysers and fuel cells. Previously, we have reported the […]

UP experts produce over 80 open videos for teaching general education

UP experts produce over 80 open videos for teaching general education

UP has made available more than 80 Open Educational Resources (OERs) on general education, thanks to the efforts of the UP Open University. Called 100 Master Voices, the project featured in multimedia formats different UP experts whose chosen topics can be used to teach the 11 core courses in general education, namely: (1) Kasaysayan ng Pilipinas, (2) Wika, Kultura at Lipunan, (3) Critical Perspectives in the Arts, (4) Philippine Arts and Culture, (5) Critical Perspectives in Communication, (6) Self and Society, (7) Ethics and Moral Reasoning in Everyday Life, (8) Living Systems: Concepts and Dynamics, (9) Probing the Physical World, […]

Number of UP Scientists for 2017-2019 is highest in 12 years

Number of UP Scientists for 2017-2019 is highest in 12 years

Seventy-one of UP’s most accomplished researchers in the physical and natural sciences, social sciences, management and economics, and engineering were officially recognized as UP Scientists for 2017-2019 in a ceremony held on 21 March at the Bahay ng Alumni in UP Diliman. The UP Scientists were chosen through the rigid selection process of the UP Scientific Productivity System where they were assessed for scientific productivity (publications and other output such as patents) and international scientific recognition. President Danilo Concepcion said in a message read by Executive Vice President Teodoro Herbosa that the awards are given in gratitude of the contributions […]

Book by UP researchers shows PH water crisis likely if institutions remain weak

Why should water management and conservation be a pressing concern for the Philippines? For UP professors Dr. Agnes C. Rola, Dr. Juan M. Pulhin and Dr. Rosalie Arcala Hall, editors of the recently-published book Water Policy in the Philippines, it is because demographic shifts, urbanization and climate change are increasingly transforming the face of water supply and demand in the country. For one, per capita water availability declined over the years, with economic growth and population increases exerting pressure on demand and decreased water sources due to the degradation of watersheds affecting supply. In fact, Rola, Pulhin and Arcala project […]

A sample of UP’s journal articles on women (2015-2018)

Here are some UP papers that tackle issues of women in the Philippines and in other parts of the world. 1. What are the roles of men and women in aquatic agricultural systems in the Philippines? 2. Trafficked women in the Philippines are likely to drink alcohol, use illegal drugs and avoid HIV tests 3. How did institutions enable women survivors to adapt to the Haiyan devastation? 4. The discovery of polymorphisms correlates with Vitamin D deficiency among post-menopausal Filipino women 5. What can we learn from women’s experiences in strengthening food security during disasters? 6. Do wanted pregnancies differ […]

Journal articles with the International Publication Award (2017)

Other lists: | 2018 | 2016 | DECEMBER 2017 SCIENCE AND TECHNOLOGY: Drywood termites prefer Moluccan sau the most and eucalyptus the least SCIENCE AND TECHNOLOGY: Because bulk ZnO single crystals can resist and recover from ion irradiation, they can be used for radiation detectors inside future fusion reactors SCIENCE AND TECHNOLOGY: The placental characteristics of cattle, which like humans carry their embryo for nine months, were studied SCIENCE AND TECHNOLOGY: Minkowski functional and cluster analysis can detect percolating channels or fluid traps in plasma-etched surfaces SCIENCE AND TECHNOLOGY: Some reefs in Samar were completely damaged and wiped-out by super […]

Journal articles with the International Publication Award (2016)

Other lists: | 2018 | 2017 | DECEMBER 2016 ARTS AND HUMANITIES: This paper analyzes the Philippine Educational Theater Association’s stage musical, Care Divas, for its figuration of the Filipino migrant worker as bakla and for its consequent queering of labor out-migration from the Philippines ARTS AND HUMANITIES: A huge international study of global causes of death has revealed that since 1990, there has been a profound change in risk factors for death SCIENCE AND TECHNOLOGY: How do senescent cells contribute to skin aging? SCIENCE AND TECHNOLOGY: Four companies that collect hospital wastes in Manila conform to the standards of the World […]